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Uncombable Hair Syndrome: When Hair Is Abnormally Unmanageable

Uncombable Hair Syndrome: When Hair Is Abnormally Unmanageable
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Uncombable Hair Syndrome

unmanageable hair


Uncombable hair syndrome, otherwise known as Pili trianguli et canaliculi, is a very rare structural abnormality of the hair follicle that causes brittle, unmanageable hair. The hair is usually coarse and will break is combed or flattened. It is white to light blonde in color. The condition typically appears during infancy.

What Causes Uncombable Hair Syndrome?

The cause of uncombable hair syndrome is a hereditary gene mutation occurring in one of the following three genes: PADI3, TGM, or TCHH3.

Types Of Uncombable Hair Syndrome

There is only one known type of uncombable hair syndrome.

Uncombable Hair Syndrome Symptoms

  • Slow-growing hair
  • Hair breakage
  • Brittle hair
  • Partial baldness
  • Hair that is coarse in texture
  • Hair that stands up straight from the scalp
  • Hair that cannot be combed down or flattened
  • Very light blonde or white hair

uncombable hair syndrome

Diagnosing Uncombable Hair Syndrome

A physical examination can be used to diagnose uncombable hair syndrome. Confirming the diagnosis usually requires a sample of the hair shaft to be examined under a microscope. If the hair shaft has a triangular or kidney-shaped appearance, it is indicative of the condition.

Treating Uncombable Hair Syndrome

There is no cure for uncombable hair syndrome, but the condition usually resolves itself as the patient reaches adulthood. Biotin supplements can help improve the health and appearance of the hair in the meantime.

 

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